spacer Crystal structure of TNF-TNFR2 complex
CATH: Protein Structure Classification
CATH code 2.60.120.40 search
Domains
3alqA00 , 3alqB00 , 3alqC00 , 3alqD00 , 3alqE00 , 3alqF00
Name Tumor necrosis factor. Chain: a, b, c, d, e, f. Fragment: soluble form. Synonym: tnf-alpha, tumor necrosis factor ligand superfamily member2, tnf-a, cachectin. Engineered: yes. Mutation: yes. Tumor necrosis factor receptor superfamily member 1b. Chain: r, s, t, u, v, w. Fragment: residues in unp 33-205. Synonym: tumor necrosis factor receptor 2, tnf-r2, tumor necrosis factor-binding protein 2, tbpii, tbp-2. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: tnf, tnfa, tnfsf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Polymers A, B, C, D, E, F
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Jelly Rolls search
Homologous superfamily Jelly Rolls search
 
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