› 3akm

X-ray diffraction
1.9Å resolution

X-ray structure of iFABP from human and rat with bound fluorescent fatty acid analogue

Released:
DOI: 10.2210/pdb3akm/pdb
PDB entry 3akm coloured by chain, front view.
PDB entry 3akm coloured by chain, side view.
PDB entry 3akm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wielens J, Laguerre AJK, Parker MW, Scanlon MJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146097 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, intestinal Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 131 amino acids
Theoretical weight: 15.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P12104 (Residues: 2-132; Coverage: 99%)
Gene names: FABP2, FABPI
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand 11D 4 x 11D
Ligand MG 4 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P21
Unit cell:
a: 51.02Å b: 79.011Å c: 63.24Å
α: 90° β: 94.48° γ: 90°
R-values:
R R work R free
0.229 0.226 0.279
Expression system: Escherichia coli BL21

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