3ac0 Summary


Crystal structure of Beta-glucosidase from Kluyveromyces marxianus in complex with glucose

The structure was published by Yoshida, E., Hidaka, M., Fushinobu, S., et al., Kitaoka, M., Katayama, T., and Kumagai, H., in 2010 in a paper entitled "Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 beta-glucosidase from Kluyveromyces marxianus." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.54 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Beta-glucosidase I.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Beta-glucosidase I D1GCC6 (1-845) (D1GCC6_KLUMA)search Kluyveromyces marxianussearch 100% 845 99%
B Beta-glucosidase I D1GCC6 (1-845) (D1GCC6_KLUMA)search Kluyveromyces marxianussearch 100% 845 99%
C Beta-glucosidase I D1GCC6 (1-845) (D1GCC6_KLUMA)search Kluyveromyces marxianussearch 100% 845 99%
D Beta-glucosidase I D1GCC6 (1-845) (D1GCC6_KLUMA)search Kluyveromyces marxianussearch 100% 845 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
D1GCC6 (1 - 845) Beta-glucosidase I Kluyveromyces marxianus

Chain Sequence family (Pfam)
A, B, C, D (D1GCC6) PF00933: Glycosyl hydrolase family 3 N terminal domainsearch, PF01915: Glycosyl hydrolase family 3 C-terminal domainsearch, PF14310: Fibronectin type III-like domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B, C, D (D1GCC6) hydrolase activitysearch hydrolase activity, hydrolyzing O-glycosyl compoundssearch hydrolase activity, acting on glycosyl bondssearch beta-glucosidase activitysearch carbohydrate metabolic processsearch metabolic processsearch

Chain InterPro annotation
A, B, C, D Glycoside hydrolase, family 3, N-terminalsearch Glycoside hydrolase family 3 C-terminal domainsearch PA14search Glycoside hydrolase superfamilysearch Glycoside hydrolase, family 3, active sitesearch Fibronectin type III-like domainsearch Glycoside hydrolase family 3search