Function and Biology Details
Reaction catalysed:
(S)-lactate + NAD(+) = pyruvate + NADH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
L-lactate dehydrogenase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-117115 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
L-lactate dehydrogenase
Molecule details ›
Chains: A, B, C, D
Length: 316 amino acids
Theoretical weight: 34.15 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 316 amino acids
Theoretical weight: 34.15 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q76NM3 (Residues: 1-316; Coverage: 100%)
Sequence domains:
- lactate/malate dehydrogenase, NAD binding domain
- lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSRRC BEAMLINE BL13B1
Spacegroup:
P21
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
