Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA-directed RNA polymerase, palm domain superfamily, Birnavirus
- Birnavirus VP3, domain 2
- Birnavirus VP3, domain 1
- Birnavirus VP3 protein
- RNA-directed RNA polymerase, C-terminal, birnavirus
- RNA-directed RNA polymerase, thumb domain superfamily, Birnavirus
- RNA-directed RNA polymerase, thumb domain, birnavirus
- DNA/RNA polymerase superfamily
1 more domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138795 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RNA-directed RNA polymerase
Molecule details ›
Chains: A, B, C
Length: 853 amino acids
Theoretical weight: 95.63 KDa
Source organism: Infectious pancreatic necrosis virus
Expression system: Escherichia coli B
UniProt:
Sequence domains:
Length: 853 amino acids
Theoretical weight: 95.63 KDa
Source organism: Infectious pancreatic necrosis virus
Expression system: Escherichia coli B
UniProt:
- Canonical:
P22173 (Residues: 1-845; Coverage: 100%)
Sequence domains:
- Birnavirus RNA dependent RNA polymerase (VP1), palm domain
- Birnavirus RNA dependent RNA polymerase (VP1), thumb domain
- Birnavirus RNA dependent RNA polymerase (VP1), C-terminal
Capsid protein VP3
Molecule details ›
Chains: D, E, F
Length: 242 amino acids
Theoretical weight: 27.24 KDa
Source organism: Infectious pancreatic necrosis virus
Expression system: Escherichia coli B
UniProt:
Length: 242 amino acids
Theoretical weight: 27.24 KDa
Source organism: Infectious pancreatic necrosis virus
Expression system: Escherichia coli B
UniProt:
- Canonical: P05844 (Residues: 735-972; Coverage: 25%)
