› 3vsq

X-ray diffraction
2Å resolution

Crystal Structure of the Cytoplasmic Domain of G-Protein-Gated Inward Rectifier Potassium Channel Kir3.2 E236R Mutant in the presence of ethanol

Released:
DOI: 10.2210/pdb3vsq/pdb
PDB entry 3vsq coloured by chain, front view.
PDB entry 3vsq coloured by chain, side view.
PDB entry 3vsq coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Inanobe A, Kurachi Y

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
G protein-activated inward rectifier potassium channel 2 Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.78 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P48542 (Residues: 199-381; Coverage: 43%)
Gene names: Girk2, Kcnj6, Kcnj7, W
Sequence domains: Inward rectifier potassium channel C-terminal domain
Structure domains: G protein-activated inward rectifier potassium channel 1

Ligands and Environments

2 bound ligands:
Ligand BME 2 x BME
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P4212
Unit cell:
a: 85.863Å b: 85.863Å c: 73.046Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.259
Expression system: Escherichia coli

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