› 3vdx

X-ray diffraction
3Å resolution

Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains

Released:
DOI: 10.2210/pdb3vdx/pdb
PDB entry 3vdx coloured by chain, front view.
PDB entry 3vdx coloured by chain, side view.
PDB entry 3vdx coloured by chain, top view.
Source organisms:
Primary publication:
Structure of a 16-nm cage designed by using protein oligomers.
Lai YT, Cascio D, Yeates TO
Science 336 1129 (2012)
PMID: 22654051

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein 1; Non-haem bromoperoxidase BPO-A2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 456 amino acids
Theoretical weight: 50.26 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29715 (Residues: 1-278; Coverage: 100%)
  • Canonical: P03485 (Residues: 3-164; Coverage: 64%)
Gene names: M, bpoA2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I222
Unit cell:
a: 122.59Å b: 127.71Å c: 204.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.228 0.281
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

38 review citations

Structural DNA nanotechnology: state of the art and future perspective.
Zhang et al. (2014)
37 more

7 mentions without citation

Protein-based antigen presentation platforms for nanoparticle vaccines.
Nguyen et al. (2021)
6 more