› 3v53

X-ray diffraction
2.9Å resolution

Crystal structure of human RBM25

Released:
DOI: 10.2210/pdb3v53/pdb
PDB entry 3v53 coloured by chain, front view.
PDB entry 3v53 coloured by chain, side view.
PDB entry 3v53 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region.
Gong D, Yang F, Li F, Qian D, Wu M, Shao Z, Wu M, Wu J, Shi Y
Biochem J 450 85-94 (2013)
PMID: 23190262

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156006 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding protein 25 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 119 amino acids
Theoretical weight: 14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49756 (Residues: 734-843; Coverage: 13%)
Gene names: RBM25, RNPC7
Sequence domains: PWI domain
Structure domains: PWI domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 81.577Å b: 86.172Å c: 197.174Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.265 0.264 0.298
Expression system: Escherichia coli

Quick links

Citations

8 citation in other articles

The splicing factor RBM25 controls MYC activity in acute myeloid leukemia.
Ge et al. (2019)
7 more

2 mentions without citation

Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region.
Gong et al. (2013)
1 more