› 3uiv

X-ray diffraction
2.2Å resolution

Human serum albumin-myristate-amantadine hydrochloride complex

Released:
DOI: 10.2210/pdb3uiv/pdb
PDB entry 3uiv coloured by chain, front view.
PDB entry 3uiv coloured by chain, side view.
PDB entry 3uiv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yang F, Ma Z, Ma L, Yang G

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chains: A, H
Molecule details ›
Chains: A, H
Length: 585 amino acids
Theoretical weight: 66.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02768 (Residues: 25-609; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1

Ligands and Environments

2 bound ligands:
Ligand MYR 13 x MYR
Ligand 308 1 x 308
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P1
Unit cell:
a: 38.27Å b: 93.516Å c: 96.217Å
α: 74.91° β: 89.75° γ: 80.04°
R-values:
R R work R free
0.23 0.226 0.29

Quick links

Citations

89 review citations

The Halogen Bond.
Cavallo et al. (2016)
88 more

1 mention without citation

Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma.
Czub et al. (2020)