› 3u1c

X-ray diffraction
1.8Å resolution

Anti-parallel dimer of N-terminal 98-aa fragment of smooth muscle tropomyosin alpha

Released:
DOI: 10.2210/pdb3u1c/pdb
PDB entry 3u1c coloured by chain, front view.
PDB entry 3u1c coloured by chain, side view.
PDB entry 3u1c coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structural analysis of smooth muscle tropomyosin α and β isoforms.
Rao JN, Rivera-Santiago R, Li XE, Lehman W, Dominguez R
J Biol Chem 287 3165-74 (2012)
PMID: 22119916

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137548 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tropomyosin alpha-1 chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.6 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04268 (Residues: 1-98; Coverage: 35%)
Gene name: TPM1
Sequence domains: Tropomyosin
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID, CHESS BEAMLINE A1
Spacegroup: P43212
Unit cell:
a: 76.654Å b: 76.654Å c: 79.693Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.246 0.284
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Tropomodulins and Leiomodins: Actin Pointed End Caps and Nucleators in Muscles.
Fowler et al. (2017)
3 more

2 mentions without citation

Structural analysis of smooth muscle tropomyosin α and β isoforms.
Rao et al. (2012)
1 more