› 3s7i

X-ray diffraction
2.35Å resolution

Crystal structure of Ara h 1

Released:
DOI: 10.2210/pdb3s7i/pdb
PDB entry 3s7i coloured by chain, front view.
PDB entry 3s7i coloured by chain, side view.
PDB entry 3s7i coloured by chain, top view.
Source organism: Arachis hypogaea
Primary publication:
Structural and immunologic characterization of Ara h 1, a major peanut allergen.
Chruszcz M, Maleki SJ, Majorek KA, Demas M, Bublin M, Solberg R, Hurlburt BK, Ruan S, Mattison CP, Mattisohn CP, Breiteneder H, Minor W
J Biol Chem 286 39318-27 (2011)
PMID: 21917921

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155002 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Allergen Ara h 1, clone P41B Chains: A, B
Molecule details ›
Chains: A, B
Length: 418 amino acids
Theoretical weight: 47.6 KDa
Source organism: Arachis hypogaea
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P43238 (Residues: 170-586; Coverage: 69%)
Sequence domains: Cupin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R3
Unit cell:
a: 92.886Å b: 92.886Å c: 231.552Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.203 0.244
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Allergy to Peanut, Soybean, and Other Legumes: Recent Advances in Allergen Characterization, Stability to Processing and IgE Cross-Reactivity.
Cabanillas et al. (2018)
7 more

8 mentions without citation

Peanut allergens.
Palladino et al. (2018)
7 more