› 3s26

X-ray diffraction
1.8Å resolution

Crystal Structure of Murine Siderocalin (Lipocalin 2, 24p3)

Released:
DOI: 10.2210/pdb3s26/pdb
PDB entry 3s26 coloured by chain, front view.
PDB entry 3s26 coloured by chain, side view.
PDB entry 3s26 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors.
Bandaranayake AD, Correnti C, Ryu BY, Brault M, Strong RK, Rawlings DJ
Nucleic Acids Res 39 e143 (2011)
PMID: 21911364

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145892 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Neutrophil gelatinase-associated lipocalin Chain: A
Molecule details ›
Chain: A
Length: 190 amino acids
Theoretical weight: 22.1 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P11672 (Residues: 21-200; Coverage: 100%)
Gene name: Lcn2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 42.89Å b: 43.96Å c: 101.92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.201 0.226
Expression system: Homo sapiens

Quick links

Citations

6 review citations

Recent advances in mammalian protein production.
Bandaranayake et al. (2014)
5 more

6 mentions without citation

Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and Therapy.
Asimakopoulou et al. (2016)
5 more