3qlu

X-ray diffraction
2.91Å resolution

Crystal structure of the GluK2/GluK5 (GluR6/KA2) ATD dimer assembly

Released:
Source organism: Rattus norvegicus
Primary publication:
Structure and assembly mechanism for heteromeric kainate receptors.
Neuron 71 319-31 (2011)
PMID: 21791290

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-154584 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glutamate receptor ionotropic, kainate 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 43.8 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q63273 (Residues: 20-406; Coverage: 40%)
Gene name: Grik5
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold
Glutamate receptor ionotropic, kainate 2 Chains: C, D
Molecule details ›
Chains: C, D
Length: 395 amino acids
Theoretical weight: 44.82 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: P42260 (Residues: 32-420; Coverage: 44%)
Gene names: Glur6, Grik2
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 65.626Å b: 139.548Å c: 195.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.197 0.256
Expression system: Homo sapiens