3p1x

X-ray diffraction
1.9Å resolution

Crystal structure of DRBM 2 domain of Interleukin enhancer-binding factor 3 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4527E

Released:
Source organism: Homo sapiens
Entry authors: Seetharaman J, Neely H, Wang D, Janjua H, Cunningham K, Owens L, Xiao R, Liu J, Baran MC, Acton TB, Montelione GT, Tong L, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-171432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin enhancer-binding factor 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 75 amino acids
Theoretical weight: 8.41 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q12906 (Residues: 520-594; Coverage: 8%)
Gene names: DRBF, ILF3, MPHOSPH4, NF90
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 107.572Å b: 24.384Å c: 71.626Å
α: 90° β: 124.84° γ: 90°
R-values:
R R work R free
0.213 0.213 0.25