› 3p0c

X-ray diffraction
2.27Å resolution

Nischarin PX-domain

Released:
DOI: 10.2210/pdb3p0c/pdb
PDB entry 3p0c coloured by chain, front view.
PDB entry 3p0c coloured by chain, side view.
PDB entry 3p0c coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Schutz P, Karlberg T, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson I, Kol S, Kotenyova T, Kouznetsova E, Moche M, Nyman T, Persson C, Siponen MI, Thorsell AG, Tresaugues L, Van Der Berg S, Wahlberg E, Welin M, Weigelt J, Nordlund P, Schuler H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-195136 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nischarin Chains: A, B
Molecule details ›
Chains: A, B
Length: 130 amino acids
Theoretical weight: 15.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y2I1 (Residues: 18-124; Coverage: 7%)
Gene names: IRAS, KIAA0975, NISCH
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 57.88Å b: 64.78Å c: 80.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.174 0.21
Expression system: Escherichia coli

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