› 3mwy

X-ray diffraction
3.7Å resolution

Crystal structure of the chromodomain-ATPase portion of the yeast Chd1 chromatin remodeler

Released:
DOI: 10.2210/pdb3mwy/pdb
PDB entry 3mwy coloured by chain, front view.
PDB entry 3mwy coloured by chain, side view.
PDB entry 3mwy coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The chromodomains of the Chd1 chromatin remodeler regulate DNA access to the ATPase motor.
Hauk G, McKnight JN, Nodelman IM, Bowman GD
Mol Cell 39 711-23 (2010)
PMID: 20832723

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-152419 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromo domain-containing protein 1 Chain: W
Molecule details ›
Chain: W
Length: 800 amino acids
Theoretical weight: 92.44 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P32657 (Residues: 142-939; Coverage: 54%)
Gene names: CHD1, SYGP-ORF4, YER164W
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand AGS 1 x AGS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P6122
Unit cell:
a: 94.333Å b: 94.333Å c: 450.088Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.265 0.262 0.318
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

37 review citations

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes.
Clapier et al. (2017)
36 more

36 mentions without citation

Snf2-family proteins: chromatin remodellers for any occasion.
Ryan et al. (2011)
35 more