› 3m9b

X-ray diffraction
3.94Å resolution

Crystal structure of the amino terminal coiled coil domain and the inter domain of the Mycobacterium tuberculosis proteasomal ATPase Mpa

Released:
DOI: 10.2210/pdb3m9b/pdb
PDB entry 3m9b coloured by chain, front view.
PDB entry 3m9b coloured by chain, side view.
PDB entry 3m9b coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Wang T, Darwin KH, Li H
Nat Struct Mol Biol 17 1352-7 (2010)
PMID: 20953180

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162085 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome-associated ATPase Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 251 amino acids
Theoretical weight: 27.49 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WQN5 (Residues: 1-234; Coverage: 38%)
Gene names: MTCY261.11c, Rv2115c, mpa
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21
Unit cell:
a: 176.787Å b: 176.652Å c: 176.633Å
α: 90° β: 90.04° γ: 90°
R-values:
R R work R free
0.276 0.275 0.304
Expression system: Escherichia coli

Quick links

Citations

27 review citations

Proteasome activators.
Stadtmueller et al. (2011)
26 more

8 mentions without citation

Bacterial Proteasomes.
Jastrab et al. (2015)
7 more