› 3m66

X-ray diffraction
1.6Å resolution

Crystal structure of human Mitochondrial Transcription Termination Factor 3

Released:
DOI: 10.2210/pdb3m66/pdb
PDB entry 3m66 coloured by chain, front view.
PDB entry 3m66 coloured by chain, side view.
PDB entry 3m66 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain.
Spåhr H, Samuelsson T, Hällberg BM, Gustafsson CM
Biochem Biophys Res Commun 397 386-90 (2010)
PMID: 20430012

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188449 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription termination factor 3, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 270 amino acids
Theoretical weight: 31.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96E29 (Residues: 148-417; Coverage: 65%)
Gene names: CGI-12, MTERF3, MTERFD1
Sequence domains: mTERF
Structure domains: Transcription termination factor 3, mitochondrial

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 139.23Å b: 32.24Å c: 70.22Å
α: 90° β: 106.59° γ: 90°
R-values:
R R work R free
0.175 0.173 0.199
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Mitochondrial DNA mutations in disease and aging.
Park et al. (2011)
9 more

4 mentions without citation

Human Mitoribosome Biogenesis and Its Emerging Links to Disease.
Lopez Sanchez et al. (2021)
3 more