› 3ldc

X-ray diffraction
1.45Å resolution

High resolution open MthK pore structure crystallized in 100 mM K+

Released:
DOI: 10.2210/pdb3ldc/pdb
PDB entry 3ldc coloured by chain, front view.
PDB entry 3ldc coloured by chain, side view.
PDB entry 3ldc coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus str. Delta H
Primary publication:
Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore.
Ye S, Li Y, Jiang Y
Nat Struct Mol Biol 17 1019-23 (2010)
PMID: 20676101

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127898 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 9.03 KDa
Source organism: Methanothermobacter thermautotrophicus str. Delta H
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 18-99; Coverage: 24%)
Gene names: MTH_1520, mthK
Sequence domains: Ion channel
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand K 5 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P4212
Unit cell:
a: 63.811Å b: 63.811Å c: 44.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.202
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Mitochondrial channels: ion fluxes and more.
Szabo et al. (2014)
13 more

28 mentions without citation

Structure of potassium channels.
Kuang et al. (2015)
27 more