› 3kwm

X-ray diffraction
2.32Å resolution

Crystal structure of ribose-5-isomerase A

Released:
DOI: 10.2210/pdb3kwm/pdb
PDB entry 3kwm coloured by chain, front view.
PDB entry 3kwm coloured by chain, side view.
PDB entry 3kwm coloured by chain, top view.
Source organism: Francisella tularensis subsp. tularensis
Entry authors: Orlikowska M, Rostankowski R, Nakka C, Hattne J, Grimshaw S, Borek D, Otwinowski Z, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
D-ribose 5-phosphate = D-ribulose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177667 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribose-5-phosphate isomerase A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 224 amino acids
Theoretical weight: 24.49 KDa
Source organism: Francisella tularensis subsp. tularensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5NFM5 (Residues: 1-224; Coverage: 100%)
Gene names: FTT_1208, rpiA
Sequence domains: Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand NA 2 x NA
Ligand PO4 3 x PO4
Ligand PEG 4 x PEG
Ligand 3GR 1 x 3GR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21212
Unit cell:
a: 182.36Å b: 73.085Å c: 75.303Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.17 0.221
Expression system: Escherichia coli

Quick links