› 3krm

X-ray diffraction
2.75Å resolution

Imp1 kh34

Released:
DOI: 10.2210/pdb3krm/pdb
PDB entry 3krm coloured by chain, front view.
PDB entry 3krm coloured by chain, side view.
PDB entry 3krm coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
ZBP1 recognition of beta-actin zipcode induces RNA looping.
Chao JA, Patskovsky Y, Patel V, Levy M, Almo SC, Singer RH
Genes Dev 24 148-58 (2010)
PMID: 20080952

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-192750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-like growth factor 2 mRNA-binding protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 163 amino acids
Theoretical weight: 18.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NZI8 (Residues: 404-566; Coverage: 28%)
Gene names: CRDBP, IGF2BP1, VICKZ1, ZBP1
Sequence domains: KH domain
Structure domains: TATA-Binding Protein

Ligands and Environments

1 bound ligand:
Ligand GOL 4 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P65
Unit cell:
a: 103.53Å b: 103.53Å c: 131.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.239
Expression system: Escherichia coli

Quick links

Citations

46 review citations

Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair.
Jung et al. (2012)
45 more

6 mentions without citation

mRNA localization in metazoans: A structural perspective.
Lazzaretti et al. (2017)
5 more