Function and Biology Details
Reaction catalysed:
ATP + H(2)O + Na(+)(Side 1) + K(+)(Side 2) = ADP + phosphate + Na(+)(Side 2) + K(+)(Side 1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Sodium/potassium-transporting ATPase subunit beta
- P-type ATPase, cytoplasmic domain N
- P-type ATPase
- Cation-transporting P-type ATPase, N-terminal
- P-type ATPase subfamily IIC, subunit alpha
- Ion-transport regulator, FXYD family
- Sodium/potassium-transporting ATPase subunit beta superfamily
- Cation-transporting P-type ATPase, C-terminal
6 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138328 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Sodium/potassium-transporting ATPase subunit alpha-1
Molecule details ›
Chains: A, C
Length: 998 amino acids
Theoretical weight: 110.32 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains:
Length: 998 amino acids
Theoretical weight: 110.32 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
P05024 (Residues: 24-1021; Coverage: 98%)
Sequence domains:
- Cation transporter/ATPase, N-terminus
- E1-E2 ATPase
- Cation transport ATPase (P-type)
- haloacid dehalogenase-like hydrolase
- Cation transporting ATPase, C-terminus
Sodium/potassium-transporting ATPase subunit beta-1
Molecule details ›
Chains: B, D
Length: 286 amino acids
Theoretical weight: 33.1 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains: Sodium / potassium ATPase beta chain
Structure domains:
Length: 286 amino acids
Theoretical weight: 33.1 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: P05027 (Residues: 18-303; Coverage: 94%)
Sequence domains: Sodium / potassium ATPase beta chain
Structure domains:
FXYD domain-containing ion transport regulator
Molecule details ›
Chains: G, H
Length: 27 amino acids
Theoretical weight: 2.95 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains: ATP1G1/PLM/MAT8 family
Length: 27 amino acids
Theoretical weight: 2.95 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: Q58K79 (Residues: 23-49; Coverage: 42%)
Sequence domains: ATP1G1/PLM/MAT8 family
