› 3k6m

X-ray diffraction
1.5Å resolution

Dynamic domains of Succinyl-CoA:3-ketoacid-coenzyme A transferase from pig heart.

Released:
DOI: 10.2210/pdb3k6m/pdb
PDB entry 3k6m coloured by chain, front view.
PDB entry 3k6m coloured by chain, side view.
PDB entry 3k6m coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase.
Coker SF, Lloyd AJ, Mitchell E, Lewis GR, Coker AR, Shoolingin-Jordan PM
Acta Crystallogr D Biol Crystallogr 66 797-805 (2010)
PMID: 20606260

Function and Biology Details

Reaction catalysed: 
Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173354 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 481 amino acids
Theoretical weight: 52.29 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q29551 (Residues: 40-520; Coverage: 93%)
Gene names: OXCT, OXCT1, SCOT
Sequence domains: Coenzyme A transferase
Structure domains: Glutaconate Coenzyme A-transferase

Ligands and Environments

2 bound ligands:
Ligand CL 2 x CL
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P21
Unit cell:
a: 73.715Å b: 133.566Å c: 102.23Å
α: 90° β: 104.98° γ: 90°
R-values:
R R work R free
0.166 0.165 0.185

Quick links

Citations

6 citation in other articles

Structural insights into adeno-associated virus serotype 5.
Govindasamy et al. (2013)
5 more

2 mentions without citation

Self-association of a highly charged arginine-rich cell-penetrating peptide.
Tesei et al. (2017)
1 more