› 3iql

X-ray diffraction
1.4Å resolution

Crystal structure of the rat endophilin-A1 SH3 domain

Released:
DOI: 10.2210/pdb3iql/pdb
PDB entry 3iql coloured by chain, front view.
PDB entry 3iql coloured by chain, side view.
PDB entry 3iql coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Trempe JF, Chen CX, Grenier K, Camacho EM, Kozlov G, McPherson PS, Gehring K, Fon EA
Mol Cell 36 1034-47 (2009)
PMID: 20064468

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128652 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endophilin-A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 71 amino acids
Theoretical weight: 7.98 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35179 (Residues: 291-352; Coverage: 18%)
Gene names: Sh3d2a, Sh3gl2, Sh3p4
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: C2
Unit cell:
a: 64.338Å b: 34.156Å c: 62.729Å
α: 90° β: 107.79° γ: 90°
R-values:
R R work R free
0.128 0.127 0.154
Expression system: Escherichia coli

Quick links

Citations

34 review citations

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles.
Sugiura et al. (2014)
33 more

7 mentions without citation

Structural basis of membrane bending by the N-BAR protein endophilin.
Mim et al. (2012)
6 more