› 3hyu

X-ray diffraction
1.67Å resolution

Crystal structure of the altitude adapted hemoglobin of guinea pig.

Released:
DOI: 10.2210/pdb3hyu/pdb
PDB entry 3hyu coloured by chain, front view.
PDB entry 3hyu coloured by chain, side view.
PDB entry 3hyu coloured by chain, top view.
Source organism: Cavia porcellus
Primary publication:
Structure of the altitude adapted hemoglobin of guinea pig in the R2-state.
Pairet B, Jaenicke E
PLoS One 5 e12389 (2010)
PMID: 20811494

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135376 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.25 KDa
Source organism: Cavia porcellus
UniProt:
  • Canonical: P01947 (Residues: 2-142; Coverage: 99%)
Gene name: HBA
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chain: B
Molecule details ›
Chain: B
Length: 146 amino acids
Theoretical weight: 15.95 KDa
Source organism: Cavia porcellus
UniProt:
  • Canonical: P02095 (Residues: 1-146; Coverage: 100%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 2 x HEM
Ligand PO4 4 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR-H
Spacegroup: C2221
Unit cell:
a: 83.54Å b: 89.95Å c: 82.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.203

Quick links

Citations

4 citation in other articles

Guinea Pig Oxygen-Sensing and Carotid Body Functional Properties.
Gonzalez-Obeso et al. (2017)
3 more

2 mentions without citation

Structure of the altitude adapted hemoglobin of guinea pig in the R2-state.
Pairet et al. (2010)
1 more