› 3gel

X-ray diffraction
2.39Å resolution

O-Methylphosphorylated Torpedo Acetylcholinesterase Obtained by Reaction with Methyl Paraoxon (AGED)

Released:
DOI: 10.2210/pdb3gel/pdb
PDB entry 3gel coloured by chain, front view.
PDB entry 3gel coloured by chain, side view.
PDB entry 3gel coloured by chain, top view.
Source organism: Tetronarce californica
Entry authors: Legler PM, Millard CB

Function and Biology Details

Reaction catalysed: 
Acetylcholine + H(2)O = choline + acetate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 532 amino acids
Theoretical weight: 60.29 KDa
Source organism: Tetronarce californica
UniProt:
  • Canonical: P04058 (Residues: 25-556; Coverage: 94%)
Gene name: ache
Sequence domains: Carboxylesterase family
Structure domains: alpha/beta hydrolase

Ligands and Environments

No bound ligands
1 modified residue:
Ligand OMH 1 x OMH

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P3121
Unit cell:
a: 111.726Å b: 111.726Å c: 136.853Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.21 0.24

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