› 3g7c

X-ray diffraction
2Å resolution

Structure of the Phosphorylation Mimetic of Occludin C-term Tail

Released:
DOI: 10.2210/pdb3g7c/pdb
PDB entry 3g7c coloured by chain, front view.
PDB entry 3g7c coloured by chain, side view.
PDB entry 3g7c coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach.
Sundstrom JM, Tash BR, Murakami T, Flanagan JM, Bewley MC, Stanley BA, Gonsar KB, Antonetti DA
J Proteome Res 8 808-17 (2009)
PMID: 19125584

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172531 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Occludin Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 13.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16625 (Residues: 416-522; Coverage: 21%)
Gene name: OCLN
Sequence domains: Occludin homology domain
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P212121
Unit cell:
a: 33.054Å b: 35.591Å c: 107.396Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.236 0.251
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Occludin: one protein, many forms.
Cummins PM. (2012)
13 more

2 mentions without citation

The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability.
Tash et al. (2012)
1 more