› 3f00

X-ray diffraction
1.36Å resolution

Crystal Structure of Synaptotagmin I C2A domain with Cu(II)

Released:
DOI: 10.2210/pdb3f00/pdb
PDB entry 3f00 coloured by chain, front view.
PDB entry 3f00 coloured by chain, side view.
PDB entry 3f00 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Guo F, Dakshinamurthy R, Thallapuranam SKK, Sakon J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149302 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptotagmin-1 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21579 (Residues: 141-266; Coverage: 30%)
Gene names: SVP65, SYT, SYT1
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

2 bound ligands:
Ligand CU 2 x CU
Ligand SO4 2 x SO4
1 modified residue:
Ligand MHO 1 x MHO

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21
Unit cell:
a: 41.647Å b: 38.363Å c: 44.016Å
α: 90° β: 98.37° γ: 90°
R-values:
R R work R free
0.203 0.201 0.244
Expression system: Escherichia coli

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