Function and Biology Details
Reactions catalysed:
Xanthine + NAD(+) + H(2)O = urate + NADH
Xanthine + H(2)O + O(2) = urate + H(2)O(2)
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
- Aldehyde oxidase/xanthine dehydrogenase-like
- CO dehydrogenase flavoprotein, C-terminal
- 2Fe-2S ferredoxin-type iron-sulfur binding domain
- Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain
- Oxidoreductase, molybdopterin binding site
- Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain
- Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily
- Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
12 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Xanthine dehydrogenase/oxidase (preferred)
PDBe Complex ID:
PDB-CPX-160414 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Xanthine dehydrogenase/oxidase
Molecule details ›
Chains: 2, A, J, S
Length: 165 amino acids
Theoretical weight: 18.13 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Structure domains:
Length: 165 amino acids
Theoretical weight: 18.13 KDa
Source organism: Bos taurus
UniProt:
- Canonical:
P80457 (Residues: 1-165; Coverage: 12%)
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase
Molecule details ›
Chains: 3, B, K, T
Length: 305 amino acids
Theoretical weight: 34.02 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Structure domains:
Length: 305 amino acids
Theoretical weight: 34.02 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P80457 (Residues: 224-528; Coverage: 23%)
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase
Molecule details ›
Chains: 4, C, L, U
Length: 762 amino acids
Theoretical weight: 83.84 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 762 amino acids
Theoretical weight: 83.84 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P80457 (Residues: 571-1332; Coverage: 57%)
Sequence domains:
- Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
- Molybdopterin cofactor-binding domain
- Molybdopterin cofactor-binding domain
