› 3egf

Solution NMR

SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY MINIMIZATION WITH RESTRAINTS

Released:
DOI: 10.2210/pdb3egf/pdb
PDB entry 3egf coloured by chain, ensemble of 16 models, front view.
PDB entry 3egf coloured by chain, ensemble of 16 models, side view.
PDB entry 3egf coloured by chain, ensemble of 16 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Montelione GT, Wüthrich K, Burgess AW, Nice EC, Wagner G, Gibson KD, Scheraga HA
Biochemistry 31 236-49 (1992)
PMID: 1731873

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor Chain: A
Molecule details ›
Chain: A
Length: 53 amino acids
Theoretical weight: 6.05 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01132 (Residues: 977-1029; Coverage: 5%)
Gene name: Egf
Sequence domains: EGF-like domain
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

9 review citations

Structure-function relationships for the EGF/TGF-alpha family of mitogens.
Groenen et al. (1994)
8 more

4 mentions without citation

Platelets Promote Metastasis via Binding Tumor CD97 Leading to Bidirectional Signaling that Coordinates Transendothelial Migration.
Ward et al. (2018)
3 more