› 3cob

X-ray diffraction
2.2Å resolution

Structural Dynamics of the Microtubule binding and regulatory elements in the Kinesin-like Calmodulin binding protein

Released:
DOI: 10.2210/pdb3cob/pdb
PDB entry 3cob coloured by chain, front view.
PDB entry 3cob coloured by chain, side view.
PDB entry 3cob coloured by chain, top view.
Source organism: Solanum tuberosum
Primary publication:
Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
Vinogradova MV, Malanina GG, Reddy VS, Reddy AS, Fletterick RJ
J Struct Biol 163 76-83 (2008)
PMID: 18513992

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174948 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin heavy chain-like protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 369 amino acids
Theoretical weight: 41.43 KDa
Source organism: Solanum tuberosum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q41460 (Residues: 884-1252; Coverage: 29%)
Gene name: 102577881
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 98.152Å b: 84.907Å c: 89.661Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.267
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Traffic control: regulation of kinesin motors.
Verhey et al. (2009)
3 more

4 mentions without citation

Structure of the complex of a mitotic kinesin with its calcium binding regulator.
Vinogradova et al. (2009)
3 more