› 3c5n

X-ray diffraction
1.8Å resolution

Structure of human TULP1 in complex with IP3

Released:
DOI: 10.2210/pdb3c5n/pdb
PDB entry 3c5n coloured by chain, front view.
PDB entry 3c5n coloured by chain, side view.
PDB entry 3c5n coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Busam RD, Lehtio L, Arrowsmith CH, Collins R, Dahlgren LG, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Hallberg BM, Herman MD, Johansson A, Johansson I, Kallas A, Karlberg T, Kotenyova T, Moche M, Nilsson ME, Nordlund P, Nyman T, Persson C, Sagemark J, Svensson L, Thorsell AG, Tresaugues L, Van den Berg S, Weigelt J, Welin M, Berglund H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tubby-related protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 246 amino acids
Theoretical weight: 28.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00294 (Residues: 291-536; Coverage: 45%)
Gene names: TUBL1, TULP1
Sequence domains: Tub family
Structure domains: Tubby Protein; Chain A

Ligands and Environments

1 bound ligand:
Ligand I3P 3 x I3P
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21
Unit cell:
a: 56.31Å b: 83.63Å c: 57.68Å
α: 90° β: 94.01° γ: 90°
R-values:
R R work R free
0.191 0.189 0.221
Expression system: Escherichia coli

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