› 3c36

X-ray diffraction
1.68Å resolution

Crystal structure of GluR5 ligand-binding core in complex with ammonium ions at 1.68 Angstrom resolution

Released:
DOI: 10.2210/pdb3c36/pdb
PDB entry 3c36 coloured by chain, front view.
PDB entry 3c36 coloured by chain, side view.
PDB entry 3c36 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Molecular basis of kainate receptor modulation by sodium.
Plested AJ, Vijayan R, Biggin PC, Mayer ML
Neuron 58 720-35 (2008)
PMID: 18549784

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149794 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, kainate 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 258 amino acids
Theoretical weight: 29.25 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P22756 (Residues: 446-559, 682-821; Coverage: 28%)
Gene names: Glur5, Grik1
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

4 bound ligands:
Ligand NH4 2 x NH4
Ligand CL 4 x CL
Ligand KAI 2 x KAI
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P41212
Unit cell:
a: 70.76Å b: 70.76Å c: 234.323Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.167 0.201
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Glutamate receptor ion channels: structure, regulation, and function.
Traynelis et al. (2010)
16 more

1 mention without citation

Molecular basis of kainate receptor modulation by sodium.
Plested et al. (2008)