› 3ba6

X-ray diffraction
2.8Å resolution

Structure of the Ca2E1P phosphoenzyme intermediate of the SERCA Ca2+-ATPase

Released:
DOI: 10.2210/pdb3ba6/pdb
PDB entry 3ba6 coloured by chain, front view.
PDB entry 3ba6 coloured by chain, side view.
PDB entry 3ba6 coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
The structural basis of calcium transport by the calcium pump.
Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, Møller JV, Nissen P
Nature 450 1036-42 (2007)
PMID: 18075584

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

3 bound ligands:
Ligand CA 3 x CA
Ligand K 1 x K
Ligand AN2 1 x AN2
1 modified residue:
Ligand PHD 1 x PHD

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2
Unit cell:
a: 162.51Å b: 75.967Å c: 152.407Å
α: 90° β: 109.01° γ: 90°
R-values:
R R work R free
0.21 0.21 0.288

Quick links

Citations

59 review citations

P-type ATPases.
Palmgren et al. (2011)
58 more

12 mentions without citation

Linking Biochemical and Structural States of SERCA: Achievements, Challenges, and New Opportunities.
Aguayo-Ortiz et al. (2020)
11 more