› 3b9r

X-ray diffraction
3Å resolution

SERCA Ca2+-ATPase E2 aluminium fluoride complex without thapsigargin

Released:
DOI: 10.2210/pdb3b9r/pdb
PDB entry 3b9r coloured by chain, front view.
PDB entry 3b9r coloured by chain, side view.
PDB entry 3b9r coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
The structural basis of calcium transport by the calcium pump.
Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, Møller JV, Nissen P
Nature 450 1036-42 (2007)
PMID: 18075584

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 994 amino acids
Theoretical weight: 109.6 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P04191 (Residues: 1-993; Coverage: 99%)
Gene name: ATP2A1
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand ALF 2 x ALF
Ligand MG 2 x MG
Ligand K 2 x K
Ligand ACP 2 x ACP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 131.98Å b: 94.43Å c: 136.18Å
α: 90° β: 107.79° γ: 90°
R-values:
R R work R free
0.186 0.185 0.235

Quick links

Citations

60 review citations

P-type ATPases.
Palmgren et al. (2011)
59 more

12 mentions without citation

Structure and mechanism of Zn2+-transporting P-type ATPases.
Wang et al. (2014)
11 more