2zy9 Summary


Improved crystal structure of magnesium transporter MgtE

The structure was published by Hattori, M., Iwase, N., Furuya, N., et al., Ito, K., Maturana, A., and Nureki, O., in 2009 in a paper entitled "Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.94 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Mg2+ transporter MgtE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Mg2+ transporter MgtE Q5SMG8 (1-450) (MGTE_THET8)search Thermus thermophilus HB8search 100% 473 90%
B Mg2+ transporter MgtE Q5SMG8 (1-450) (MGTE_THET8)search Thermus thermophilus HB8search 100% 473 90%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q5SMG8 (1 - 450) Mg2+ transporter MgtE Thermus thermophilus HB8

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q5SMG8) CBS-domainsearch, Magnesium transporter mgtEsearch PF00571: CBS domainsearch, PF01769: Divalent cation transportersearch, PF03448: MgtE intracellular N domainsearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A, B (Q5SMG8) membranesearch plasma membranesearch integral component of membranesearch magnesium ion transportsearch cation transmembrane transportsearch transportsearch cation transportsearch magnesium ion bindingsearch metal ion bindingsearch magnesium ion transmembrane transporter activitysearch cation transmembrane transporter activitysearch protein homodimerization activitysearch

Chain InterPro annotation
A, B CBS domainsearch SLC41 divalent cation transporters, integral membrane domainsearch Magnesium transporter, MgtE intracellular domainsearch Magnesium transporter MgtEsearch