Crystal structures of rat Catechol-O-Methyltransferase complexed with coumarine-based inhibitor
The structure was published by Tsuji, E., Okazaki, K., and Takeda, K., in 2009 in a paper entitled "Crystal structures of rat catechol-O-methyltransferase complexed with coumarine-based inhibitor" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Catechol O-methyltransferase. This molecule has the UniProt identifier P22734 (COMT_RAT). The sample contained 223 residues which is < 90% of the natural sequence. Out of 223 residues 212 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: