Lyn Tyrosine Kinase Domain-Dasatinib complex
The structure was published by Williams, N.K., Lucet, I.S., Klinken, S.P., Ingley, E., and Rossjohn, J., in 2009 in a paper entitled "Crystal Structures of the Lyn Protein Tyrosine Kinase Domain in Its Apo- and Inhibitor-bound State" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Tyrosine-protein kinase Lyn. This molecule has the UniProt identifier P25911 (LYN_MOUSE). The sample contained 279 residues which is < 90% of the natural sequence. Out of 279 residues 259 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: