Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609
The structure was published by Kukimoto-Niino, M., Yoshikawa, S., Takagi, T., et al., Kadowaki, T., Minokoshi, Y., and Yokoyama, S., in 2011 in a paper entitled "Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Calcium/calmodulin-dependent protein kinase kinase 2. This molecule has the UniProt identifier Q96RR4 (KKCC2_HUMAN). The sample contained 298 residues which is < 90% of the natural sequence. Out of 298 residues 256 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: