TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity; R1antTNF-T8
The structure was published by Mukai, Y., Nakamura, T., Yoshioka, Y., et al., Kamada, H., Yamagata, Y., and Tsutsumi, Y., in 2009 in a paper entitled "Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.83 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Tumor necrosis factor.
The molecule most likely forms homotrimers.
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This entry contains 1 unique UniProt protein: