spacer TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity; R1antTNF-T8
CATH: Protein Structure Classification
CATH code 2.60.120.40 search
Domains
2zpxA00 , 2zpxB00 , 2zpxC00
Name Tumor necrosis factor. Chain: a, b, c. Fragment: unp residues 77-233.Synonym: tnf-alpha, tumor necrosis factor ligand superfamily member 2,tnf-a, cachectin, antagonistic tnf mutant (r1anttnf-t8). Engineered:yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: tnf, tnfa, tnfsf2. Expressed in: escherichia coli. Expression_system_taxid:562.
Polymers A, B, C
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Jelly Rolls search
Homologous superfamily Jelly Rolls search
 
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