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EBI PDBe PDBeView

PDBe Entry: 2zkm view

Crystal Structure of Phospholipase C Beta 2
Summary
Header Hydrolasesearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.62 Å, R-factor: 19.7%, Free R-factor: 21.3%, Spacegroup: P 21 21 21
Released 12/08/2008, deposition: 26/03/2008, last revision: 24/02/2009
Authors Hicks, S.N.search; Jezyk, M.R.search; Gershberg, S.search; Seifert, J.P.search; Harden, T.K.search; Sondek, J.search
Primary citation General and versatile autoinhibition of PLC isozymes
MOL.CELLsearch vol:31, pag:383-394 (2008) [PubMed ID 18691970 ]search
Keywords phospholipase Csearch, phosphoinositide phospholipasesearch, PLC-Beta-2search, Calciumsearch, Coiled coilsearch, Hydrolasesearch, Lipid degradationsearch, Metal-bindingsearch, Transducersearch
EC 3.1.4.11 ExPASy BRENDA search (X)
Organism Homo sapiens(human) 9606search(X)
UniProt 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-2) (PLC-beta-2) Q00722search (X)
Solvent X
Polymers
Id Name Type UniProt Residues Observed
X 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 Protein Q00722 (PLCB2_HUMAN)search
 799 88%
Heterogens
Id Name Ligands
X CALCIUM ION CA search
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