2zkc Summary

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Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z

A publication describing this structure is not available. The depositing authors are Matsushima, A.search; Kakuta, Y.search; Teramoto, T.search; Shimohigashi, Y.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Estrogen-related receptor gamma. This molecule has the UniProt identifier P62508 (ERR3_HUMAN)search. The sample contained 244 residues which is < 90% of the natural sequence. Out of 244 residues 226 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Estrogen-related receptor gamma P62508 (222-458) (ERR3_HUMAN)search Homo sapienssearch < 90% 244 93%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P62508 (222 - 458) Estrogen-related receptor gamma Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Retinoid X Receptorsearch Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P62508) regulation of transcription, DNA-templatedsearch steroid hormone mediated signaling pathwaysearch steroid hormone receptor activitysearch DNA bindingsearch sequence-specific DNA binding transcription factor activitysearch nucleussearch

Chain InterPro annotation
A Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Nuclear hormone receptor, ligand-bindingsearch