Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with 4-alpha-cumylphenol, a bisphenol A derivative
The structure was published by Matsushima, A., Teramoto, T., Okada, H., et al., Tokunaga, T., Kakuta, Y., and Shimohigashi, Y., in 2008 in a paper entitled "ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Estrogen-related receptor gamma. This molecule has the UniProt identifier P62508 (ERR3_HUMAN). The sample contained 244 residues which is < 90% of the natural sequence. Out of 244 residues 227 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: