2z5n

X-ray diffraction
3.2Å resolution

Complex of Transportin 1 with hnRNP D NLS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187824 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transportin-1 Chain: A
Molecule details ›
Chain: A
Length: 890 amino acids
Theoretical weight: 101.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92973 (Residues: 9-898; Coverage: 99%)
Gene names: KPNB2, MIP1, TNPO1, TRN
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Heterogeneous nuclear ribonucleoprotein D0 Chain: B
Molecule details ›
Chain: B
Length: 24 amino acids
Theoretical weight: 2.77 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q14103 (Residues: 332-355; Coverage: 7%)
Gene names: AUF1, HNRNPD, HNRPD

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 69.683Å b: 118.954Å c: 151.208Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.232 0.295
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided