2yw8

X-ray diffraction
3Å resolution

Crystal structure of human RUN and FYVE domain-containing protein

Released:
Source organism: Homo sapiens
Entry authors: Wang H, Kishishita S, Murayama K, Takemoto C, Terada T, Shirouzu M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-188761 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RUN and FYVE domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 9.35 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q96T51 (Residues: 627-708; Coverage: 12%)
Gene names: RABIP4, RUFY1, ZFYVE12
Sequence domains: FYVE zinc finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P4332
Unit cell:
a: 115.15Å b: 115.15Å c: 115.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.224
Expression system: Not provided