2yuq Summary


Solution structure of the SH3 domain of human Tyrosine-protein kinase ITK/TSK

A publication describing this structure is not available. The depositing authors are Abe, H.search; Miyamoto, K.search; Tochio, N.search; Sato, M.search; Koshiba, S.search; Harada, T.search; Watanabe, S.search; Kigawa, T.search; Yokoyama, S.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Tyrosine-protein kinase ITK/TSK. This molecule has the UniProt identifier Q08881 (ITK_HUMAN)search. The sample contained 85 residues which is < 90% of the natural sequence. Out of 85 residues 85 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Tyrosine-protein kinase ITK/TSK Q08881 (162-239) (ITK_HUMAN)search Homo sapienssearch < 90% 85 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q08881 (162 - 239) Tyrosine-protein kinase ITK/TSK Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH2 domainsearch, SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch Spectrin alpha chain, SH3 domainsearch