2yd2 Summary

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CRYSTAL STRUCTURE OF THE N-TERMINAL IG1-2 MODULE OF HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE SIGMA

The structure was published by Coles, C.H., Shen, Y., Tenney, A.P., et al., Jones, E.Y., Flanagan, J.G., and Aricescu, A.R., in 2011 in a paper entitled "Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.552 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S. This molecule has the UniProt identifier Q13332 (PTPRS_HUMAN)search. The sample contained 214 residues which is < 90% of the natural sequence. Out of 214 residues 197 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S Q13332 (30-244) (PTPRS_HUMAN)search Homo sapienssearch < 90% 214 92%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q13332 (30 - 244) RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S Homo sapiens

Chain Sequence family (Pfam)
A Immunoglobulin I-set domainsearch
Chain InterPro annotation
A Immunoglobulin subtype 2search Immunoglobulin-like domainsearch Immunoglobulin I-setsearch Immunoglobulin-like foldsearch