CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) IN COMPLEX WITH THE HA155 BORONIC ACID INHIBITOR
There is a Quite Interesting Protein Structure article for this entry.
The structure was published by Hausmann, J., Kamtekar, S., Christodoulou, E., et al., Morris, A.J., Moolenaar, W.H., and Perrakis, A., in 2011 in a paper entitled "Structural Basis of Substrate Discrimination and Integrin Binding by Autotaxin." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2. This molecule has the UniProt identifier Q64610 (ENPP2_RAT). The sample contained 862 residues which is < 90% of the natural sequence. Out of 862 residues 757 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: