› 2xrb

X-ray diffraction
2.5Å resolution

Structure of the N-terminal four domains of the complement regulator Rat Crry

Released:
DOI: 10.2210/pdb2xrb/pdb
PDB entry 2xrb coloured by chain, front view.
PDB entry 2xrb coloured by chain, side view.
PDB entry 2xrb coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structures of the rat complement regulator CrrY.
Roversi P, Johnson S, Caesar JJ, McLean F, Leath KJ, Tsiftsoglou SA, Morgan BP, Harris CL, Sim RB, Lea SM
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 739-43 (2011)
PMID: 21795784

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement component receptor 1-like protein Chain: A
Molecule details ›
Chain: A
Length: 290 amino acids
Theoretical weight: 31.93 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q63135 (Residues: 1-288; Coverage: 48%)
Gene names: Cr1l, Crry
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

2 bound ligands:
Ligand SO4 3 x SO4
Ligand EDO 13 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 21.77Å b: 105.339Å c: 152.281Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.237
Expression system: Escherichia coli BL21

Quick links

Citations

3 citation in other articles

The CD46-Jagged1 interaction is critical for human TH1 immunity.
Le Friec et al. (2012)
2 more

4 mentions without citation

C1q and Mannose-Binding Lectin Interact with CR1 in the Same Region on CCP24-25 Modules.
Jacquet et al. (2018)
3 more